Enteroaggregative E. coli (EAEC)

Stages of pathogenesis of EAEC

Enteroaggregative E. coli (EAEC) are a heterogeneous collection of strains characterized by their autoagglutination in a “stacked-brick” arrangement over the epithelium of the small intestine and, in some cases, the colon. EAEC strains are currently defined as E. coli strains that do not secrete enterotoxins LT or ST and that adhere to HEp-2 cells in an AA pattern. The prevalence of disease caused by EAEC is unclear because a single molecular marker for these bacteria has not been discovered. Genes encoding adhesins, …Read more